4. Kālidāsa in Ceylon, 522

Prehistoric Archreology in Ceylon

Pterygium in Ceylon.

The geographical situation of Ceylon led Cameron (I965) to suggest that the pterygium rate there would range from 5-5 to over io per cent., but the actual incidence appears to be much less for reasons which are discussed below. The incidence of pterygium has not been closely studied, first perhaps because it rarely causes blindness, secondly because the world's earliest eye hospitals were situa...

Childhood in Ceylon

Lead poisoning in childhood has been reported mainly from Japan, France, the United States, Great Britain, and Australia. Attention is drawn in this paper to the incidence of lead intoxication in childhood in Ceylon, seen and diagnosed within the past three years. Whereas in past reports the principal mode of lead intoxication in childhood has been from ingestion, in the present series inhalati...

Yaws control in Ceylon.

Ceylon is a small island, 25,332 square miles in extent: its greatest length is 270 miles and its greatest width 140 miles. It is situated to the south of India lying between 5° 53'and 9°51'N. and between 70° 42' and 810 55' E. Most of the country is flat, the hilly parts being restricted to a small central area. The annual rainfall ranges from about 20 in. in the dry zone to 150-200 in. in the...

Dmd062596 510..522

Clopidogrel is a prodrug that needs to be converted to its active metabolite (clopi-H4) in two sequential cytochrome P450 (P450)dependent steps. In the present study, a dynamic physiologically based pharmacokinetic (PBPK) model was developed in Simcyp for clopidogrel and clopi-H4 using a specific sequential metabolite module in four populations with phenotypically different CYP2C19 activity (po...